Synthesis, Characterization and antimicrobial activity of Co(II), Ni(II) and Cu(II) complexes of schiff bases derived from 4-aminoactophenone and furane 2- carboxaldehyde
Publication Date : 06/03/2016
The new three complexes of Co(II), Ni(II) and Cu(II) with a schiff base 2,4-Furyliminobenzylacetophenone(FIBA) derived from the condensation of 4-aminoactophenone and furane 2- carboxaldehyde in methanol have been synthesized. The ligand and their metal complexes have been characterized by their elemental analysis, molar conductance, magnetic moments, I.R., NMR, electronic spectral studies; purity of the compounds has been ascertained by determining their repeated melting points of a sample, running TLC for single spot. The ligand and their metal complexes were screened for antibacterial and antifungal activities against bacteria Staphylococcus aureus (ATCC 25923), and Staphylococcus aureus (ATCC 3160) and common fungi; Candida albicance (227) and Staphylococcus cereviscae (361) by the agar well diffusion method. The Schiff base showed varied antibacterial and antifungal activity against one or more strains respectively and their activity was enhanced on coordination or chelation. Key words: Schiff base ligand, complexes, I.R., NMR, Electronic spectra, Magnetic moment and Biocidal studies.
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