Asymmetric Mach–Zehnder Interferometer Using Biosensors
Publication Date : 30/01/2018
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We present a study of Aflatoxin M1 detection by photonic biosensors based on Si3N4 Asymmetric Mach–Zehnder Interferometer (aMZI) functionalized with antibodies fragments (Fabʹ). We measured a best volumetric sensitivity of 104 rad/RIU, leading to a Limit of Detection below 5x10-7 RIU. On sensors functionalized with Fabʹ, we performed specific and non-specific sensing measurements at various toxin concentrations. Reproducibility of the measurements and re-usability of the sensor were also investigated.
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